MK-0674

目录号: A21558
cathepsin K inhibitor
MK-0674 是一种强效、口服生物利用度高且选择性的 cathepsin K 抑制剂,其 IC50 为 0.4 nM,相较于 Cat B、Cat F、Cat L 和 Cat S,显示出 1156、1465、11857 和 243 倍的选择性。
Grouped product items
规格 价格 库存 数量
1mg
¥2,205.00
现货
2mg
¥4,200.00
现货
5mg
¥6,685.00
现货
10mg
¥10,675.00
现货
25mg
¥15,855.00
现货
50mg
¥20,825.00
现货
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生物活性
Discription MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.
产品信息
目录号 A21558
分子式 C26H27F6N3O2
分子量 527.5
CAS号 887781-62-6
SMILES N#CC1(CC1)NC([C@H](CC(C)(C)F)N[C@@H](C2=CC=C(C3=CC=C(C=C3)[C@@H](O)C(F)F)C=C2)C(F)(F)F)=O
其他名称 MK0674, MK 0674
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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