MK-0674

Name: MK-0674
SKU: A21558
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A21558

cathepsin K 抑制剂

MK-0674 是一种强效、口服生物利用度高且选择性的 cathepsin K 抑制剂，其 IC50 为 0.4 nM，相较于 Cat B、Cat F、Cat L 和 Cat S，显示出 1156、1465、11857 和 243 倍的选择性。

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Grouped product items
规格	价格	库存
1mg	¥2,205.00	现货
2mg	¥4,200.00	现货
5mg	¥6,685.00	现货
10mg	¥10,675.00	现货
25mg	¥15,855.00	现货
50mg	¥20,825.00	现货
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Data Sheet

SDS

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生物活性

Discription	MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.

产品信息

目录号	A21558
分子式	C26H27F6N3O2
分子量	527.5
CAS号	887781-62-6
SMILES	N#CC1(CC1)NC([C@H](CC(C)(C)F)N[C@@H](C2=CC=C(C3=CC=C(C=C3)[C@@H](O)C(F)F)C=C2)C(F)(F)F)=O
其他名称	MK0674, MK 0674
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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