MK-0752

Name: MK-0752
SKU: A11194
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A11194

Gamma-secretase 抑制剂

MK-0752 抑制 Notch 信号通路，这可能导致在 Notch 信号通路 过度激活的肿瘤细胞中诱导生长停滞和凋亡。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
5mg	¥1,015.00	现货
10mg	¥1,715.00	现货
25mg	¥3,010.00	现货
50mg	¥3,815.00	现货
100mg	¥6,195.00	现货
*10mM 1mL in DMSO**	¥1,190.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	MK-0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated.

产品信息

目录号	A11194
分子式	C21H21ClF2O4S
分子量	442.9
CAS号	471905-41-6
SMILES	C1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
其他名称	MK0752
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	85 mg/mL (191.91 mM)
	Water	Insoluble
	Ethanol	43 mg/mL (97.08 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.58 mL	112.89 mL	225.78 mL
0.5 mM	4.52 mL	22.58 mL	45.16 mL
1 mM	2.26 mL	11.29 mL	22.58 mL
5 mM	0.45 mL	2.26 mL	4.52 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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