产品详情
MK-0752抑制Notch信号通路,这可能会导致Notch信号通路被过度激活的肿瘤细胞诱导生长停滞和凋亡。
In vitro (25°C) | DMSO | 85 mg/mL (191.91 mM) | |
Water | Insoluble | ||
Ethanol | 43 mg/mL (97.08 mM) | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.58 mL | 112.89 mL | 225.78 mL |
0.5 mM | 4.52 mL | 22.58 mL | 45.16 mL |
1 mM | 2.26 mL | 11.29 mL | 22.58 mL |
5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11194 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 442.9 |
Formula | C21H21ClF2O4S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 471905-41-6 |
Synonyms | MK0752 |
SMILES | C1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl |
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