MK-0941
目录号: A20823
allosteric glucokinase activator
MK-0941 是一种强效的、口服活性的、异构酶激活剂,对重组人源葡萄糖激酶具有激活作用,其 EC50 分别为在 2.5 mM 和 10 mM 葡萄糖存在下的 240 nM 和 65 nM。MK-0941 在治疗2型糖尿病方面具有潜力。
Discription | MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes. |
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目录号 | A20823 |
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分子式 | C22H28N4O9S2 |
分子量 | 556.61 |
CAS号 | 1137916-97-2 |
SMILES | CS(=O)(O)=O.O=C(NC1=NN(C)C=C1)C2=CC(O[C@@H](C)CO)=CC(OC3=CC=C(S(=O)(CC)=O)N=C3)=C2 |
其他名称 | MK0941, MK 0941 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2