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MK-0974 (Telcagepant)是人和恒河猴CGRP受体的有效和选择性拮抗剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.65 mL | 88.26 mL | 176.52 mL |
| 0.5 mM | 3.53 mL | 17.65 mL | 35.3 mL |
| 1 mM | 1.77 mL | 8.83 mL | 17.65 mL |
| 5 mM | 0.35 mL | 1.77 mL | 3.53 mL |
*The above data is based on the productmolecular weight 566.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11255 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 566.5 |
| Formula | C26H27F5N6O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 781649-09-0 |
| Synonyms | Telcagepant |
| SMILES | C1C[C@H](C(=O)N(C[C@@H]1C2=C(C(=CC=C2)F)F)CC(F)(F)F)NC(=O)N3CCC(CC3)N4C5=C(NC4=O)N=CC=C5 |
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