MK-1064
目录号: A16360
OX2 Ant激动剂
MK-1064 是一种强效、选择性且可口服的Orexin OX2 受体拮抗剂,有望用于治疗失眠。
Discription | MK-1064 is a potent, selective and orally active Orexin OX2 Receptor Antagonist for potential treatment of insomnia. | |||||
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Targets |
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Cell Research |
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目录号 | A16360 |
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分子式 | C24H20ClN5O3 |
分子量 | 461.91 |
CAS号 | 1207253-08-4 |
SMILES | O=C(C1=CC(C2=CC(Cl)=CN=C2)=CN=C1C3=NC=CC=C3)NCC4=NC(OC)=C(OC)C=C4 |
其他名称 | MK1064, MK 1064 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 87 mg/mL (188.35 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.65 mL | 108.25 mL | 216.49 mL |
0.5 mM | 4.33 mL | 21.65 mL | 43.3 mL |
1 mM | 2.16 mL | 10.82 mL | 21.65 mL |
5 mM | 0.43 mL | 2.16 mL | 4.33 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2