MK-2461
目录号: A11753
c-Met 抑制剂
MK-2461,一种新型多靶点激酶抑制剂,优先抑制激活的 c-Met 受体。
Discription | MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor. | |||||
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Targets |
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Cell Research |
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目录号 | A11753 |
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分子式 | C24H25N5O5S |
分子量 | 495.6 |
CAS号 | 917879-39-1 |
SMILES | CN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)NS(=O)(=O)N(C)C[C@@H]5COCCO5)C(=O)C3=C2 |
其他名称 | MK2461 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 95 mg/mL (191.7 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80, pH 4 | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.18 mL | 100.89 mL | 201.78 mL |
0.5 mM | 4.04 mL | 20.18 mL | 40.36 mL |
1 mM | 2.02 mL | 10.09 mL | 20.18 mL |
5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2