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MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂，IC50为0.12 nM。
靶点信息
| CGRP | ||||
| 0.12 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.83 mL | 84.16 mL | 168.32 mL |
| 0.5 mM | 3.37 mL | 16.83 mL | 33.66 mL |
| 1 mM | 1.68 mL | 8.42 mL | 16.83 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.37 mL |
*The above data is based on the productmolecular weight 594.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10598 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 594.1 |
| Formula | C31H30ClF2N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 957116-20-0 |
| Synonyms | MK3207, MK-3207 |
| SMILES | C1CCC2(C1)C(=O)N([C@@H](CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(C[C@@]6(C5)C7=C(NC6=O)N=CC=C7)C=C4.Cl |
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