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MK-3207是一种有效且口服可生物利用的CGRP受体拮抗剂（IC50 = 0.12 nM；Ki = 0.024 nM）；对人类AM1，AM2，CTR和AMY3具有高度选择性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.93 mL | 89.67 mL | 179.34 mL |
| 0.5 mM | 3.59 mL | 17.93 mL | 35.87 mL |
| 1 mM | 1.79 mL | 8.97 mL | 17.93 mL |
| 5 mM | 0.36 mL | 1.79 mL | 3.59 mL |
*The above data is based on the productmolecular weight 557.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15165 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 557.59 |
| Formula | C31H29F2N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 957118-49-9 |
| Synonyms | MK3207, MK 3207 |
| SMILES | C1CCC2(C1)C(=O)N(C(CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(CC6(C5)C7=C(NC6=O)N=CC=C7)C=C4 |
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