MK-3903

Name: MK-3903
SKU: A17063
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A17063

AMPK activator

MK-3903 是一种强效且选择性的 AMPK 激活剂（EC50 = 8 nM）。MK-3903 在小鼠口服给药后，在小鼠肝脏中显示出强大的靶向作用，从而改善了小鼠的脂质代谢和胰岛素敏感性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥455.00	现货
10mg	¥805.00	现货
25mg	¥1,330.00	现货
50mg	¥2,555.00	现货
100mg	¥4,270.00	现货
200mg	¥6,090.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

MK-3903 is a potent and selective AMPK activator (EC50 = 8 nM). MK-3903 exhibited robust target engagement in mouse liver following oral dosing, leading to improved lipid metabolism and insulin sensitization in mice.

Targets

Target	Value

产品信息

目录号	A17063
分子式	C27H19ClN2O3
分子量	454.91
CAS号	1219737-12-8
SMILES	O=C(O)C1=CC(OC2=NC3=CC(C4=CC=C(C5=CC=CC=C5)C=C4)=C(Cl)C=C3N2)=CC=C1C
其他名称	MK3903, MK 3903
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	82 mg/mL (180.26 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.98 mL	109.91 mL	219.82 mL
0.5 mM	4.4 mL	21.98 mL	43.96 mL
1 mM	2.2 mL	10.99 mL	21.98 mL
5 mM	0.44 mL	2.2 mL	4.4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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