MK-5108 (VX-689)

Name: MK-5108 (VX-689)
SKU: A11410
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A11410

Aurora A Kinase 抑制剂

1 篇发表文献

MK-5108，亦称为 VX-689，是一种与 ATP结合位点 竞争的 aurora A激酶 抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥525.00	现货
10mg	¥910.00	现货
25mg	¥1,610.00	现货
50mg	¥2,555.00	现货
100mg	¥3,850.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用MK-5108 (VX-689)发表的1篇文献

Wei TW, .et al. , Cancer Res, 2017, Jan 15;77(2):494-508 PMID: 28069801

生物活性

Discription

MK-5108, also known as VX-689, is a competitive inhibitor of the ATP-binding site of aurora A kinase.

Targets

Target	Value

产品信息

目录号	A11410
分子式	C22H21ClFN3O3S
分子量	461.9
CAS号	1010085-13-8
SMILES	C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O
其他名称	MK5108, VX689
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	81 mg/mL (175.35 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose+0.2% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.65 mL	108.25 mL	216.5 mL
0.5 mM	4.33 mL	21.65 mL	43.3 mL
1 mM	2.16 mL	10.82 mL	21.65 mL
5 mM	0.43 mL	2.16 mL	4.33 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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