MKC8866
目录号: A19523
IRE1 RNase inhibitor
MKC8866,一种水杨醛类似物,是一种强效、选择性的 IRE1 RNase 抑制剂,其在人体体外的 IC50 为 0.29 μM。
Discription | MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29?μM in human vitro. |
---|
目录号 | A19523 |
---|---|
分子式 | C18H19NO7 |
分子量 | 361.35 |
CAS号 | 1338934-59-0 |
SMILES | O=CC1=C(O2)C(C(C)=C(CC(N3CCOCC3)=O)C2=O)=CC(OC)=C1O |
其他名称 | MKC-8866; MKC 8866; IRE1-IN-8866; IRE1IN8866; IRE1 IN 8866; IRE1-IN8866; IRE1-IN 8866; IRE1IN-8866; IRE1IN 8866 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 3 mg/mL (8.3 mM) | |
Water | <1 mg/mL | ||
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.67 mL | 138.37 mL | 276.74 mL |
0.5 mM | 5.53 mL | 27.67 mL | 55.35 mL |
1 mM | 2.77 mL | 13.84 mL | 27.67 mL |
5 mM | 0.55 mL | 2.77 mL | 5.53 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2