ML 145
目录号: A19953
GPR35/CXCR8 antagonist
ML 145 是一种选择性的 GPR35/CXCR8 拮抗剂,其 IC50/EC50 为 20.1 nM,但对相关的 GPR55 孤儿受体无效。GPR35 在免疫系统的多种细胞中表达,可能作为炎症性疾病治疗的潜在靶点。
Discription | ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease. | |||||
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Cell Research |
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目录号 | A19953 |
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分子式 | C24H22N2O5S2 |
分子量 | 482.57 |
CAS号 | 1164500-72-4 |
SMILES | CC(/C=C(S1)/C(N(CCCC(NC2=CC(O)=C(C(O)=O)C=C2)=O)C1=S)=O)=C\C3=CC=CC=C3 |
其他名称 | ML145, ML-145 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2