ML 145

目录号: A19953
GPR35/CXCR8 antagonist
ML 145 是一种选择性的 GPR35/CXCR8 拮抗剂,其 IC50/EC50 为 20.1 nM,但对相关的 GPR55 孤儿受体无效。GPR35 在免疫系统的多种细胞中表达,可能作为炎症性疾病治疗的潜在靶点。
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规格 价格 库存 数量
1mg
¥350.00
现货
2mg
¥595.00
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5mg
¥910.00
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10mg
¥1,470.00
现货
25mg
¥2,520.00
现货
50mg
¥3,780.00
现货
100mg
¥5,460.00
现货
200mg
¥7,875.00
现货
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生物活性
Discription ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A19953
分子式 C24H22N2O5S2
分子量 482.57
CAS号 1164500-72-4
SMILES CC(/C=C(S1)/C(N(CCCC(NC2=CC(O)=C(C(O)=O)C=C2)=O)C1=S)=O)=C\C3=CC=CC=C3
其他名称 ML145, ML-145
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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