ML 161
目录号: A13495
PAR1 抑制剂
ML-161 是一种抑制蛋白酶激活受体 1（PAR1）介导的血小板激活的抑制剂（对人血小板 P-选择素表达的抑制 IC50 = 0.26 μM）。
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生物活性
| Discription | ML-161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). |
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产品信息
| 目录号 | A13495 |
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| 分子式 | C17H17BrN2O2 |
| 分子量 | 361.23 |
| CAS号 | 423735-93-7 |
| SMILES | CCCC(=O)NC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2Br |
| 其他名称 | ML-161, ML161 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 68 mg/mL (188.24 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.68 mL | 138.42 mL | 276.83 mL |
| 0.5 mM | 5.54 mL | 27.68 mL | 55.37 mL |
| 1 mM | 2.77 mL | 13.84 mL | 27.68 mL |
| 5 mM | 0.55 mL | 2.77 mL | 5.54 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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