ML-792
目录号: A16832
SAE inhibitor
ML-792 是一种强效且选择性的 SAE 抑制剂,在细胞实验中具有纳摩尔级的效力。ML-792 选择性地阻断 SAE 酶活性 和总 SUMOylation,从而减少癌细胞的增殖。
Discription | ML-792 is a potent and selective SAE inhibitor with nanomolar potency in cellular assays. ML-792 selectively blocks SAE enzyme activity and total SUMOylation, thus decreasing cancer cell proliferation. | |||||
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Cell Research |
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目录号 | A16832 |
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分子式 | C21H23BrN6O5S |
分子量 | 551.42 |
CAS号 | 1644342-14-2 |
SMILES | O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=NN(CC4=CC=CC(Br)=C4)C=C3)=O)C1)(N)=O |
其他名称 | ML 792, ML792 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 90 mg/mL (163.22 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.13 mL | 90.67 mL | 181.35 mL |
0.5 mM | 3.63 mL | 18.13 mL | 36.27 mL |
1 mM | 1.81 mL | 9.07 mL | 18.13 mL |
5 mM | 0.36 mL | 1.81 mL | 3.63 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2