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ML167是一种高度选择性的Cdc2样激酶4（Clk4）抑制剂。
靶点信息
| CLK4 | CLK1 | CLK2 | Dyrk1B | |
| 136 nM | 1522 nM | 1648 nM | 4420 nM |
| In vitro | DMSO | 64 mg/mL (190.83 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 12 mg/mL (35.78 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.82 mL | 149.09 mL | 298.19 mL |
| 0.5 mM | 5.96 mL | 29.82 mL | 59.64 mL |
| 1 mM | 2.98 mL | 14.91 mL | 29.82 mL |
| 5 mM | 0.6 mL | 2.98 mL | 5.96 mL |
*The above data is based on the productmolecular weight 335.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14297 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 335.36 |
| Formula | C19H17N3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1285702-20-6 |
| Synonyms | CID 44968231, ML 167 |
| SMILES | CC1=CC=C(O1)N(C)C2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO |
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