ML355
目录号: A18349
12-Lipoxygenase (12-LOX) inhibitor
ML355 是一种强效且选择性的 12-脂氧合酶（12-LOX）抑制剂，其 IC50 为 0.34 μM，对相关的脂氧合酶和环氧合酶显示出极佳的选择性，并具有良好的 ADME 特性。
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生物活性
| Discription | ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties. | ||
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| Targets |
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产品信息
| 目录号 | A18349 |
|---|---|
| 分子式 | C21H19N3O4S2 |
| 分子量 | 441.52 |
| CAS号 | 1532593-30-8 |
| SMILES | O=S(C1=CC=C(NCC2=CC=CC(OC)=C2O)C=C1)(NC3=NC4=CC=CC=C4S3)=O |
| 其他名称 | ML 355, ML-355 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 86 mg/mL (194.78 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.65 mL | 113.25 mL | 226.49 mL |
| 0.5 mM | 4.53 mL | 22.65 mL | 45.3 mL |
| 1 mM | 2.26 mL | 11.32 mL | 22.65 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.53 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1532593-30-8 | 1532593-30-8 供应商 | 1532593-30-8 花费 | 1532593-30-8 生产商 | 订购 1532593-30-8 | 1532593-30-8 代理商