ML390

Name: ML390
SKU: A13386
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A13386

DHODH inhibitor

ML390 是一种强效的二氢乳清酸脱氢酶 (DHODH) 抑制剂。ML390 是一种诱导骨髓分化的物质，能够在小鼠（ER-HoxA9）和人类（U937 和 THP1）急性髓性白血病（AML）模型中引起骨髓分化。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥420.00	现货
25mg	¥805.00	现货
50mg	¥1,260.00	现货
100mg	¥2,310.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription

ML390 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor. ML390 is an inducer of myeloid differentiation and causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) acute myeloid leukemia (AML) models.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13386
分子式	C21H21F3N2O3
分子量	406.4
CAS号	2029049-79-2
SMILES	O=C(NCCC(N[C@H]1C(C=CC=C2)=C2CCC1)=O)C3=CC=C(OC(F)(F)F)C=C3
其他名称	ML 390, ML-390
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	72 mg/mL (177.16 mM)
	Water	Insoluble
	Ethanol	53 mg/mL (130.41 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.61 mL	123.03 mL	246.06 mL
0.5 mM	4.92 mL	24.61 mL	49.21 mL
1 mM	2.46 mL	12.3 mL	24.61 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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