MLi-2

目录号: A20530
brain penetrant LRRK2 inhibitor
MLi-2 是一种效力强大、高度选择性、可口服、能穿透大脑的 LRRK2 抑制剂,其 IC50 为 0.76 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥385.00
现货
2mg
¥560.00
现货
5mg
¥910.00
现货
10mg
¥1,400.00
现货
25mg
¥3,150.00
现货
50mg
¥4,795.00
现货
100mg
¥6,860.00
现货
10mM * 1mL in DMSO
¥980.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription MLi-2 is a potent, highly selective, orally available, brain penetrant inhibitor of LRRK2 with an IC50 of 0.76 nM.
产品信息
目录号 A20530
分子式 C21H25N5O2
分子量 379.46
CAS号 1627091-47-7
SMILES C[C@@](C1)([H])O[C@](C)([H])CN1C2=CC(C3=NNC4=CC=C(OC5(C)CC5)C=C43)=NC=N2
其他名称 MLi 2; MLi2
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 72 mg/mL (189.74 mM)
Water 72 mg/mL (189.74 mM)
Ethanol 8 mg/mL (21.08 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.35 mL 131.77 mL 263.53 mL
0.5 mM 5.27 mL 26.35 mL 52.71 mL
1 mM 2.64 mL 13.18 mL 26.35 mL
5 mM 0.53 mL 2.64 mL 5.27 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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