目录号: A10602
Proteasome 抑制剂
Ixazomib Citrate (MLN9708) Analogue 是一种蛋白酶体抑制剂,它抑制蛋白酶体的活性,阻断蛋白酶体通常执行的靶向蛋白质降解。
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生物活性
Discription | Ixazomib Citrate (MLN9708) Analogue is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome. |
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Targets |
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产品信息
目录号 | A10602 |
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分子式 | C20H23BCl2N2O9 |
分子量 | 517.1 |
CAS号 | 1201902-80-8 |
SMILES | B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro (25°C) | DMSO | 85 mg/mL (164.36 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 0.5% hydroxyethyl cellulose | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.34 mL | 96.69 mL | 193.39 mL |
0.5 mM | 3.87 mL | 19.34 mL | 38.68 mL |
1 mM | 1.93 mL | 9.67 mL | 19.34 mL |
5 mM | 0.39 mL | 1.93 mL | 3.87 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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