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Molibresib besylate (GSK 525762C; I-BET 762 besylate) is a BET bromodomain inhibitor with IC50 of 32.5-42.5 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.18 mL | 85.9 mL | 171.8 mL |
| 0.5 mM | 3.44 mL | 17.18 mL | 34.36 mL |
| 1 mM | 1.72 mL | 8.59 mL | 17.18 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.44 mL |
*The above data is based on the productmolecular weight 582.07. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21855 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 582.07 |
| Formula | C28H28ClN5O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1895049-20-3 |
| Synonyms | GSK 525762C, GSK-525762C, GSK525762C; I-BET 762 besylate, I-BET762, I-BET-762 |
| SMILES | ClC1=CC=C(C2=N[C@@H](CC(NCC)=O)C3=NN=C(C)N3C4=CC=C(OC)C=C24)C=C1.O=S(C5=CC=CC=C5)(O)=O |
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