Monastrol
目录号: A11976
Kinesin-5(KIF11) 抑制剂
Monastrol 是一种强效的、可渗透细胞的非微管蛋白相互作用的有丝分裂抑制剂。Monastrol 通过与有丝分裂运动蛋白 Eg5结合来阻断有丝分裂（IC5N/A = 14 μM），Eg5 是维持纺锤体两极性所必需的马达蛋白。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity. | ||
|---|---|---|---|
| Targets |
|
产品信息
| 目录号 | A11976 |
|---|---|
| 分子式 | C14H16N2O3S |
| 分子量 | 292.4 |
| CAS号 | 329689-23-8 |
| SMILES | CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 54 mg/mL (184.71 mM) | |
| Water | Insoluble | ||
| Ethanol | 54 mg/mL (184.71 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.2 mL | 171 mL | 342 mL |
| 0.5 mM | 6.84 mL | 34.2 mL | 68.4 mL |
| 1 mM | 3.42 mL | 17.1 mL | 34.2 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 Monastrol | Monastrol 供应商 | Monastrol 花费 | Monastrol 生产商 | 订购 Monastrol | Monastrol 代理商
| 购买 329689-23-8 | 329689-23-8 供应商 | 329689-23-8 花费 | 329689-23-8 生产商 | 订购 329689-23-8 | 329689-23-8 代理商