Motesanib Diphosphate (AMG-706)
目录号: A10608
VEGFR 抑制剂
Motesanib,也被称为 AMG-706,是一种口服多激酶抑制剂,它选择性地针对 VEGF 受体、血小板源生长因子受体 和 Kit 受体。
Discription | Motesanib, also known as AMG-706, is an orally administered multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors, and Kit receptors. | ||
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目录号 | A10608 |
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分子式 | C22H23N5O.2H3PO4 |
分子量 | 569.4 |
CAS号 | 857876-30-3 |
SMILES | CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C.OP(=O)(O)O.OP(=O)(O)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 88 mg/mL (154.54 mM) | |
Water | Warmed: 17 mg/mL (29.85 mM) | ||
Ethanol | Insoluble | ||
In vivo | Saline | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.56 mL | 87.81 mL | 175.62 mL |
0.5 mM | 3.51 mL | 17.56 mL | 35.12 mL |
1 mM | 1.76 mL | 8.78 mL | 17.56 mL |
5 mM | 0.35 mL | 1.76 mL | 3.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2