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MPEP HCl是对mGlu5a受体亚型（IC50 = 36 nM）的有效，高度选择性的非竞争性拮抗剂，但在浓度高达30 uM的mGlu1b受体上无激动剂或拮抗剂活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 43.54 mL | 217.68 mL | 435.35 mL |
| 0.5 mM | 8.71 mL | 43.54 mL | 87.07 mL |
| 1 mM | 4.35 mL | 21.77 mL | 43.54 mL |
| 5 mM | 0.87 mL | 4.35 mL | 8.71 mL |
*The above data is based on the productmolecular weight 229.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13236 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 229.7 |
| Formula | C14H11N.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 219911-35-0 |
| Synonyms | MPEP hydrochloride |
| SMILES | CC1=CC=CC(=N1)C#CC2=CC=CC=C2.Cl |
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