MRK 560

Name: MRK 560
SKU: A15304
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A15304

γ-secretase 抑制剂

MRK 560 是一种口服生物利用度的 伽玛分泌酶抑制剂，能显著减少大鼠大脑和脑脊液中的阿尔茨海默病β淀粉样蛋白。此外，MRK 560 确认了利用大鼠评估 伽玛分泌酶抑制剂 对中枢神经系统中活体内 Abeta(40) 水平影响的有效性。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥560.00	现货
25mg	¥980.00	现货
50mg	¥1,890.00	现货
100mg	¥3,290.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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Data Sheet

SDS

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生物活性

Discription

MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15304
分子式	C19H17ClF5NO4S2
分子量	517.92
CAS号	677772-84-8
SMILES	C1CC(CCC1NS(=O)(=O)C(F)(F)F)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
其他名称	MRK-560, MRK560
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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