MS023
目录号: A12585
PRMT1 抑制剂
MS023 是一种强效的 PRMTs 1,3,4,6,和 8 抑制剂（各自的 IC50 分别为 30, 119, 83, 8, 和 8 nM），这些酶负责 精氨酸残基的非对称二甲基化。
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生物活性
| Discription | MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues. | ||
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产品信息
| 目录号 | A12585 |
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| 分子式 | C17H25N3O |
| 分子量 | 287.4 |
| CAS号 | 1831110-54-3 |
| SMILES | NCCN(C)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2 |
| 其他名称 | MS-023, MS 023 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 50 mg/mL (173.96 mM) | |
| Water | Insoluble | ||
| Ethanol | 50 mg/mL (173.96 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.79 mL | 173.97 mL | 347.95 mL |
| 0.5 mM | 6.96 mL | 34.79 mL | 69.59 mL |
| 1 mM | 3.48 mL | 17.4 mL | 34.79 mL |
| 5 mM | 0.7 mL | 3.48 mL | 6.96 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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