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Muscimol hydrobromide是抗抑郁药氟西汀的活性代谢产物,可抑制5-羟色胺的摄取,pKi值为7.35.1。诺氟西汀的S-对映体的5-羟色胺再摄取阻断效能比R-对映体高20倍(分别为pKis = 7.86与6.51)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 51.28 mL | 256.4 mL | 512.79 mL |
0.5 mM | 10.26 mL | 51.28 mL | 102.56 mL |
1 mM | 5.13 mL | 25.64 mL | 51.28 mL |
5 mM | 1.03 mL | 5.13 mL | 10.26 mL |
*The above data is based on the productmolecular weight 195.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13459 |
---|---|
作用机制 | Agonist (激动剂) |
M. Wt | 195.01 |
Formula | C4H6N2O2.BrH |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 18174-72-6 |
SMILES | C1=C(ONC1=O)CN.Br |
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