NADPH oxidase

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Apocynin (Acetovanillone)

Catalog No. A11989
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NADPH-oxidase 抑制剂

Apocynin (Acetovanillone)是NADPH氧化酶抑制剂。了解更多

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- Liling Su, .et al. Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity, Ecotoxicol Environ Saf, 2022, Jun 1;237:113519 PMID: 35453021
- Shimizu S, .et al. Angiotensin II, a stress-related neuropeptide in the CNS, facilitates micturition reflex in rats, Br J Pharmacol, 2018, Sep;175(18):3727-3737 PMID: 29981238
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Diphenyleneiodonium chloride

Catalog No. A13359
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GPR3 激动剂/NOS/ NADPH oxidases 抑制剂

Diphenyleneiodonium是一种有效的不可逆的巨噬细胞抑制剂NOS2（iNOS）和内皮细胞NOS3（eNOS）抑制剂。了解更多

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ML 171

Catalog No. A13360
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NOX1 抑制剂

ML 171是一种有效的、选择性的NADPH-oxidase抑制剂，对NOX1、NOX2、NOX3、NOX4和xanthine oxidase的IC50分别为0.25 μM, 5 μM, 3μM, 5 μM 和 5.5 μM。了解更多

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GKT137831

Catalog No. A14433
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NOX1/4 抑制剂

GKT137831是针对NOX1和NOX4酶的一流抑制剂。了解更多

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- Chia-Hui Huang, .et al. Arsenic Trioxide-Induced p38 MAPK and Akt Mediated MCL1 Downregulation Causes Apoptosis of BCR-ABL1-positive Leukemia Cells, Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283
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APX-115

Catalog No. A18737
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Nox inhibitor

APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury. 了解更多

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GSK2795039

Catalog No. A20998
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NOX2 inhibitor

GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 reduces apoptosis. 了解更多

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