Naftopidil 2HCl

Name: Naftopidil 2HCl
SKU: A10619

目录号: A10619

5-HT1A and α1-adrenergic receptor 拮抗剂

Naftopidil 2HCl Chemical Structure

CAS NO. 57149-08-3

Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂，IC50分别为0.1μM和0.2μM。

库存：现货

规格	价格	数量
25 mg	￥ 245.00
50 mg	￥ 350.00
100 mg	￥ 630.00
500 mg	￥ 2,310.00
10mM * 1mL in DMSO	￥ 462.00

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生物活性

Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂，IC50分别为0.1μM和0.2μM。

靶点信息

5-HT1A	α1-adrenergic receptor
0.1 μM	0.2 μM

溶解度 *

In vitro (25°C)	DMSO	35 mg/mL (75.2 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.29 mM)
In vivo	0.5% CMC	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.49 mL	107.43 mL	214.87 mL
0.5 mM	4.3 mL	21.49 mL	42.97 mL
1 mM	2.15 mL	10.74 mL	21.49 mL
5 mM	0.43 mL	2.15 mL	4.3 mL

*The above data is based on the productmolecular weight 465.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10619
作用机制	Antagonist (拮抗剂)
M. Wt	465.4
Formula	C24H28N2O3.2HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	57149-08-3
Synonyms	Flivas, KT-611, Avishot
SMILES	COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl