Nampt-IN-3

目录号: A19769
NAMPT inhibitor
Nampt-IN-3(化合物35)同时抑制烟酰胺磷酸核糖转移酶(NAMPT)和组蛋白去乙酰化酶(HDAC),其半抑制浓度(IC50)分别为31纳摩尔和55纳摩尔。Nampt-IN-3有效诱导细胞凋亡和自噬,并最终导致细胞死亡。
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规格 价格 库存 数量
1mg
¥2,205.00
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5mg
¥2,520.00
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10mg
¥4,060.00
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25mg
¥7,770.00
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50mg
¥12,460.00
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100mg
¥17,465.00
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生物活性
Discription Nampt-IN-3 (Compound 35) simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A19769
分子式 C29H25N7O2
分子量 503.55
CAS号 2121591-52-2
SMILES O=C(C1=CC=C(C2=CN(CC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3)N=N2)C=C1)NCC5=CC=CN=C5
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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