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NBI-74330 is a potent antagonist for CXCR3, and exhibits potent inhibition of (125I)CXCL10 and (125I)CXCL11 specific binding with Ki of 1.5 and 3.2 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.51 mL | 82.57 mL | 165.13 mL |
| 0.5 mM | 3.3 mL | 16.51 mL | 33.03 mL |
| 1 mM | 1.65 mL | 8.26 mL | 16.51 mL |
| 5 mM | 0.33 mL | 1.65 mL | 3.3 mL |
*The above data is based on the productmolecular weight 605.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21158 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 605.58 |
| Formula | C32H27F4N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 855527-92-3 |
| Synonyms | NBI74330, NBI 74330 |
| SMILES | O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(F)C(C(F)(F)F)=C5 |
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