Nebivolol
目录号: A13738
Beta-1 adrenergic receptor blocker
Nebivolol 是一种选择性抑制 Beta-1 肾上腺素能受体 的药物,其 IC50 为 0.8 nM。
Discription | Nebivolol is a selective inhibits Beta-1 adrenergic receptor with IC50 of 0.8 nM |
---|
目录号 | A13738 |
---|---|
分子式 | C22H25F2NO4 |
分子量 | 405.44 |
CAS号 | 118457-14-0 |
SMILES | C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O |
其他名称 | Nebilet, Bystolic, R 065824, R065824, R-065824 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 75 mg/mL (184.99 mM) | |
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.66 mL | 123.32 mL | 246.65 mL |
0.5 mM | 4.93 mL | 24.66 mL | 49.33 mL |
1 mM | 2.47 mL | 12.33 mL | 24.66 mL |
5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2