Nedisertib
目录号: A17055
DNA-PK 抑制剂
Nedisertib，也被称为 M-3814、MSC2490484A，是一种口服可用的DNA依赖性蛋白激酶（DNA-PK）抑制剂，具有潜在的抗肿瘤和化疗/放疗增敏活性。
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生物活性
| Discription | Nedisertib, also known as M-3814, MSC2490484A, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities. |
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产品信息
| 目录号 | A17055 |
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| 分子式 | C24H21ClFN5O3 |
| 分子量 | 481.91 |
| CAS号 | 1637542-33-6 |
| SMILES | COC1=CC=C([C@@H](O)C2=CC(C3=C(C=CC(N4CCOCC4)=C5)C5=NC=N3)=C(F)C=C2Cl)N=N1 |
| 其他名称 | MSC2490484A, MSC-2490484A; MSC 2490484A, M3814, M-3814, M 3814 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 86 mg/mL (178.45 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (4.15 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.75 mL | 103.75 mL | 207.51 mL |
| 0.5 mM | 4.15 mL | 20.75 mL | 41.5 mL |
| 1 mM | 2.08 mL | 10.38 mL | 20.75 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.15 mL |
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| 购买 1637542-33-6 | 1637542-33-6 供应商 | 1637542-33-6 花费 | 1637542-33-6 生产商 | 订购 1637542-33-6 | 1637542-33-6 代理商