Nemorexant
目录号: A12685
orexin receptor 拮抗剂
Nemorexant(ACT-541468)是一种强效的orexin受体拮抗剂,源自专利WO2015083094A1中的化合物示例7,其对Ox1受体和Ox2受体的IC50分别为2纳摩尔和3纳摩尔。
Discription | Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively. |
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目录号 | A12685 |
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分子式 | C23H23ClN6O2 |
分子量 | 450.92 |
CAS号 | 1505484-82-1 |
SMILES | C[C@](CCC1)(C2=NC3=CC=C(Cl)C(C)=C3N2)N1C(C4=C(N5N=CC=N5)C=CC(OC)=C4)=O |
其他名称 | ACT-541468, ACT 541468, ACT541468 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2