Nemorexant

Name: Nemorexant
SKU: A12685

目录号: A12685

Orexin receptor antagonist

Nemorexant Chemical Structure

CAS NO. 1505484-82-1

Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 630.00
5 mg	￥ 1,890.00
10 mg	￥ 3,220.00
50 mg	￥ 9,660.00

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生物活性

Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.18 mL	110.88 mL	221.77 mL
0.5 mM	4.44 mL	22.18 mL	44.35 mL
1 mM	2.22 mL	11.09 mL	22.18 mL
5 mM	0.44 mL	2.22 mL	4.44 mL

*The above data is based on the productmolecular weight 450.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12685
作用机制	Antagonist (拮抗剂)
M. Wt	450.92
Formula	C23H23ClN6O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1505484-82-1
Synonyms	ACT-541468, ACT 541468, ACT541468
SMILES	C[C@](CCC1)(C2=NC3=CC=C(Cl)C(C)=C3N2)N1C(C4=C(N5N=CC=N5)C=CC(OC)=C4)=O