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Nepicastat HCl

目录号: A11172
DBH 抑制剂
Nepicastat hydrochloride 是一种多巴胺 β-羟化酶的抑制剂,这种酶催化多巴胺转化为去甲肾上腺素。
Grouped product items
规格 价格 库存 数量
5mg
¥315.00
现货
10mg
¥560.00
现货
25mg
¥1,050.00
现货
50mg
¥1,855.00
现货
100mg
¥3,290.00
现货
500mg
¥7,315.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Nepicastat HCl发表的3篇文献
  • Jianxia Sun, .et al. , Respir Res, 2024, Sep 28;25(1):347 PMID: 39342317
  • Melina C Acosta, .et al. , Behav Brain Res, 2024, Jun 17:471:115116 PMID: 38897419
  • Melina C Acosta, .et al. , Horm Behav, 2022, Jan;137:105086 PMID: 34808463
  • 生物活性
    Discription

    Nepicastat hydrochloride is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

    Targets
    Target Value
    产品信息
    目录号 A11172
    分子式 C14H15F2N3S.HCl
    分子量 331.81
    CAS号 170151-24-3
    SMILES C1CC2=C(C=C(C=C2C[C@H]1N3C(=CNC3=S)CN)F)F.Cl
    其他名称 RS-25560-197, SYN117
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 59 mg/mL (177.8 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% CMC Na 19 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.14 mL 150.69 mL 301.38 mL
    0.5 mM 6.03 mL 30.14 mL 60.28 mL
    1 mM 3.01 mL 15.07 mL 30.14 mL
    5 mM 0.6 mL 3.01 mL 6.03 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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