Nepicastat HCl

Name: Nepicastat HCl
SKU: A11172

目录号: A11172

DBH 抑制剂

Product Citations (1)

Nepicastat HCl Chemical Structure

CAS NO. 170151-24-3

Nepicastat HCl是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。

库存：现货

规格	价格	数量
5 mg	￥ 420.00
10 mg	￥ 700.00
50 mg	￥ 2,100.00
100 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 693.00

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生物活性

Nepicastat HCl是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。

靶点信息

Bovine dopamine-beta-hydroxylase	Human dopamine-beta-hydroxylase
8.5 nM	9 nM

溶解度 *

In vitro (25°C)	DMSO	59 mg/mL (177.8 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% CMC Na	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.14 mL	150.69 mL	301.38 mL
0.5 mM	6.03 mL	30.14 mL	60.28 mL
1 mM	3.01 mL	15.07 mL	30.14 mL
5 mM	0.6 mL	3.01 mL	6.03 mL

*The above data is based on the productmolecular weight 331.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11172
作用机制	Inhibitor (抑制剂)
M. Wt	331.81
Formula	C14H15F2N3S.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	170151-24-3
Synonyms	RS-25560-197, SYN117
SMILES	C1CC2=C(C=C(C=C2C[C@H]1N3C(=CNC3=S)CN)F)F.Cl