Neratinib (HKI-272)

Name: Neratinib (HKI-272)
SKU: A10638
Price: 175 CNY
Rating: 5 (3 reviews)

目录号: A10638

HER2 抑制剂

3 篇发表文献

Neratinib (HKI-272) 是一种酪氨酸激酶抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥385.00	现货
50mg	¥560.00	现货
100mg	¥840.00	现货
200mg	¥1,330.00	现货
500mg	¥2,240.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Neratinib (HKI-272)发表的3篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259

Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961

生物活性

Discription

Neratinib (HKI-272) is a tyrosine kinase inhibitor.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10638
分子式	C30H29ClN6O3
分子量	557
CAS号	698387-09-6
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 4 mg/mL (7.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.95 mL	89.77 mL	179.53 mL
0.5 mM	3.59 mL	17.95 mL	35.91 mL
1 mM	1.8 mL	8.98 mL	17.95 mL
5 mM	0.36 mL	1.8 mL	3.59 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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