NGI-1
目录号: A18706
OST inhibitor
NGI-1 (ML414) 是一种强效的寡糖基转移酶（OST）抑制剂，直接针对并阻断 OST 催化亚单位 STT3A 和 STT3B 的功能。NGI-1 是一种可渗透细胞的抑制剂，能有效降低病毒感染性，而不影响细胞活力。
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生物活性
| Discription | NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability. |
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产品信息
| 目录号 | A18706 |
|---|---|
| 分子式 | C17H22N4O3S2 |
| 分子量 | 394.51 |
| CAS号 | 790702-57-7 |
| SMILES | O=C(NC1=NC=C(C)S1)C2=CC(S(=O)(N(C)C)=O)=CC=C2N3CCCC3 |
| 其他名称 | NGI1; NGI 1; ML414; ML 414; ML-414; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 69 mg/mL (174.89 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.35 mL | 126.74 mL | 253.48 mL |
| 0.5 mM | 5.07 mL | 25.35 mL | 50.7 mL |
| 1 mM | 2.53 mL | 12.67 mL | 25.35 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.07 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 790702-57-7 | 790702-57-7 供应商 | 790702-57-7 花费 | 790702-57-7 生产商 | 订购 790702-57-7 | 790702-57-7 代理商