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NGP-555是一种γ-分泌酶调节剂，具有选择性机制，可减少Abeta 42，同时提高较短的Abeta形式，例如Abeta 37和38。
| In vitro | DMSO | 38 mg/mL (93.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.37 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.6 mL | 123 mL | 245.99 mL |
| 0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
| 1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
*The above data is based on the productmolecular weight 406.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17051 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 406.52 |
| Formula | C23H23FN4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1304630-27-0 |
| Synonyms | NGP555, NGP 555 |
| SMILES | FC1=CC(C2=CSC(NC3=CC(CC)=C(C)C=C3C)=N2)=CC=C1N4C=C(C)N=C4 |
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