Nicergoline

目录号: A17422

α1A-adrenoceptor antagonist

Nicergoline 是一种麦角衍生物,用于治疗老年痴呆和其他血管起源的疾病。它已被发现可以增加心智敏捷性,并增强清晰度和感知力。它降低血管阻力并增加大脑中的动脉血流,改善大脑细胞对氧气和葡萄糖的利用。它在身体的其他区域,特别是肺部,也具有类似的血管活性特性。Nicergoline 用于治疗诸如脑血栓和动脉粥样硬化、四肢的动脉阻塞、雷诺病、血管性偏头痛和视网膜病变等血管疾病。
Grouped product items
规格 价格 库存 数量
5mg
¥175.00
现货
10mg
¥280.00
现货
25mg
¥385.00
现货
50mg
¥490.00
现货
100mg
¥700.00
现货
200mg
¥980.00
现货
500mg
¥1,680.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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生物活性
Discription Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs. Nicergoline is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.
产品信息
目录号 A17422
分子式 C24H26BrN3O3
分子量 484.386
CAS号 27848-84-6
SMILES O=C(C1=CC(Br)=CN=C1)OC[C@H](C[C@]23OC)CN(C)[C@]3([H])CC4=CN(C)C5=C4C2=CC=C5
其他名称 Nicergoline, Nicotergoline, Nimergoline, Sermion
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 19 mg/mL (39.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.64 mL 103.22 mL 206.45 mL
0.5 mM 4.13 mL 20.64 mL 41.29 mL
1 mM 2.06 mL 10.32 mL 20.64 mL
5 mM 0.41 mL 2.06 mL 4.13 mL
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