NIK SMI1
目录号: A19308
NIK 抑制剂
NIK SMI1 是一种强效、选择性的 NF-κB 诱导激酶 (NIK) 抑制剂,它能抑制 NIK 催化的 ATP 水解为 ADP,IC50 为 0.23±0.17 nM。
Discription | NIK SMI1 is a potent, selective NF-κB inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM. | |||||
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Cell Research |
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目录号 | A19308 |
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分子式 | C20H19N3O4 |
分子量 | 365.38 |
CAS号 | 1660114-31-7 |
SMILES | O=C(N)C1=NC(C2=CC=CC(C#C[C@]3(O)CCN(C)C3=O)=C2)=CC(OC)=C1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 64 mg/mL (175.16 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 27.37 mL | 136.84 mL | 273.69 mL |
0.5 mM | 5.47 mL | 27.37 mL | 54.74 mL |
1 mM | 2.74 mL | 13.68 mL | 27.37 mL |
5 mM | 0.55 mL | 2.74 mL | 5.47 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2