Ningetinib

目录号: A17042
tyrosine kinase inhibitor
Ningetinib 是一种多激酶抑制剂,能够抑制 c-MetVEGFR2/KDRAxl,其 IC50 值分别为 19、37 和 11 nM。
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规格 价格 库存 数量
2mg
¥245.00
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5mg
¥420.00
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10mg
¥630.00
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25mg
¥1,330.00
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50mg
¥2,345.00
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100mg
¥4,060.00
现货
10mM * 1mL in DMSO
¥490.00
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生物活性
Discription Ningetinib is a multi-kinase inhibitor that inhibits c-Met, VEGFR2/KDR, and Axl with IC50s value of 19, 37, and 11 nM, respectively.
Targets
Target Value
产品信息
目录号 A17042
分子式 C31H29FN4O5
分子量 556.6
CAS号 1394820-69-9
SMILES FC1=CC(NC(C2=C(C)N(C)N(C3=CC=CC=C3)C2=O)=O)=CC=C1OC4=CC=NC5=C4C=CC(OCC(O)(C)C)=C5
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 18 mg/mL (32.34 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.97 mL 89.83 mL 179.66 mL
0.5 mM 3.59 mL 17.97 mL 35.93 mL
1 mM 1.8 mL 8.98 mL 17.97 mL
5 mM 0.36 mL 1.8 mL 3.59 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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