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Nintedanib esylate

目录号: A16197
RTK 抑制剂
Nintedanib 是一种强效的多重受体酪氨酸激酶(RTKs)和非受体酪氨酸激酶(nRTKs)抑制剂。
Grouped product items
规格 价格 库存 数量
5mg
¥210.00
现货
10mg
¥315.00
现货
25mg
¥420.00
现货
50mg
¥490.00
现货
100mg
¥700.00
现货
200mg
¥1,120.00
现货
500mg
¥2,275.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Nintedanib esylate发表的2篇文献
  • Majid Momeny, .et al. , Eur J Pharmacol, 2020, 882:173298
  • Thibaut Fourniols, .et al. , Int J Pharm, 2020, Jun 30;584:119337 PMID: 32371002
  • 生物活性
    Discription Nintedanib is a potent inhibitor of multiple receptor tyrosine kinases (RTKs) and non-receptor tyrosine kinases (nRTKs).
    Targets
    Target Value
    产品信息
    目录号 A16197
    分子式 C33H39N5O7S
    分子量 649.76
    CAS号 656247-18-6
    SMILES O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)OC.CCS(=O)(O)=O
    其他名称 BIBF-1120 esylate
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 89 mg/mL (136.97 mM)
    Water 89 mg/mL (136.97 mM)
    Ethanol 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 15.39 mL 76.95 mL 153.9 mL
    0.5 mM 3.08 mL 15.39 mL 30.78 mL
    1 mM 1.54 mL 7.7 mL 15.39 mL
    5 mM 0.31 mL 1.54 mL 3.08 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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