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Niraparib tosylate

Niraparib tosylate

Name: Niraparib tosylate
SKU: A16618

目录号: A16618

PARP1/PARP2 inhibitor

Product Citations (1)

Niraparib tosylate Chemical Structure

CAS NO. 1038915-73-9

Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively.

库存：现货

规格	价格	数量
5 mg	￥ 441.00
10 mg	￥ 763.00
50 mg	￥ 2,254.00
100 mg	￥ 4,508.00

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生物活性

Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively.

溶解度 *

In vitro	DMSO	86 mg/mL (174.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.3 mL	101.5 mL	203.01 mL
0.5 mM	4.06 mL	20.3 mL	40.6 mL
1 mM	2.03 mL	10.15 mL	20.3 mL
5 mM	0.41 mL	2.03 mL	4.06 mL

*The above data is based on the productmolecular weight 492.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16618
作用机制	Inhibitor (抑制剂)
M. Wt	492.59
Formula	C26H28N4O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1038915-73-9
Synonyms	MK-4827 tosylate
SMILES	NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.O=S(C5=CC=C(C)C=C5)(O)=O