Nisoldipine
目录号: A10646
calcium channel blocker
尼索地平(BAY-k 5552;Sular)是一种属于二氢吡啶类的钙通道阻滞剂,特异性针对L型Cav1.2,IC50为10纳摩尔。
Discription | Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
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目录号 | A10646 |
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分子式 | C20H24N2O6 |
分子量 | 388.41 |
CAS号 | 63675-72-9 |
SMILES | O=C(C1=C(C)NC(C)=C(C(OCC(C)C)=O)C1C2=CC=CC=C2[N+]([O-])=O)OC |
其他名称 | BAY-k 5552 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 72 mg/mL (185.37 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 56 mg/mL (144.17 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.75 mL | 128.73 mL | 257.46 mL |
0.5 mM | 5.15 mL | 25.75 mL | 51.49 mL |
1 mM | 2.57 mL | 12.87 mL | 25.75 mL |
5 mM | 0.51 mL | 2.57 mL | 5.15 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2