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Nivocasan (GS-9450)是一种新型的caspase抑制剂，已在纤维化/凋亡动物模型中证明了其肝保护活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.07 mL | 120.36 mL | 240.73 mL |
| 0.5 mM | 4.81 mL | 24.07 mL | 48.15 mL |
| 1 mM | 2.41 mL | 12.04 mL | 24.07 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14100 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 415.41 |
| Formula | C21H22FN3O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 908253-63-4 |
| Synonyms | GS 9450,LB 84451 GS 9450,LB 84451 |
| SMILES | CC(C)[C@]1(CC(=NO1)C2=CC=CC3=C2C=NC=C3)C(=O)N[C@H]4CC(=O)O[C@@]4(CF)O |
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