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NK314是一种新型的合成苯并[c]菲啶生物碱,具有很强的抗肿瘤活性。它抑制拓扑异构酶II活性并稳定拓扑异构酶II-DNA可裂解的复合物。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.26 mL | 126.32 mL | 252.63 mL |
0.5 mM | 5.05 mL | 25.26 mL | 50.53 mL |
1 mM | 2.53 mL | 12.63 mL | 25.26 mL |
5 mM | 0.51 mL | 2.53 mL | 5.05 mL |
*The above data is based on the productmolecular weight 395.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13993 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 395.83 |
Formula | C22H18ClNO4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 208237-49-4 |
Synonyms | NK-314, NK 314 |
SMILES | OC1=C(OC)C=CC2=C(C=CC3C4C=C5C(OCO5)=C3)C4=[N+]6C(CCC6)=C12.[Cl-] |
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