NMS-1286937

Name: NMS-1286937
SKU: A13045

目录号: A13045

PLK 抑制剂

NMS-1286937 Chemical Structure

CAS NO. 1034616-18-6

NMS-1286937是一种小分子Polo样激酶1（PLK1）抑制剂，具有潜在的抗肿瘤活性。

库存：现货

规格	价格	数量
10 mg	￥ 700.00
25 mg	￥ 1,260.00
50 mg	￥ 1,820.00

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生物活性

NMS-1286937是一种小分子Polo样激酶1（PLK1）抑制剂，具有潜在的抗肿瘤活性。

靶点信息

PLK1	PLK2	PLK3
2 nM	>10 μM	>10 μM

溶解度 *

In vitro	DMSO	Warmed: 38 mg/mL (71.36 mM)
	Water	Insoluble
	Ethanol	Warmed: 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.78 mL	93.89 mL	187.79 mL
0.5 mM	3.76 mL	18.78 mL	37.56 mL
1 mM	1.88 mL	9.39 mL	18.78 mL
5 mM	0.38 mL	1.88 mL	3.76 mL

*The above data is based on the productmolecular weight 532.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13045
作用机制	Inhibitor (抑制剂)
M. Wt	532.52
Formula	C24H27F3N8O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1034616-18-6
Synonyms	NMS1286937, NMS-P937
SMILES	CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO