NMS-873

Name: NMS-873
SKU: A12377
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A12377

p97 抑制剂

1 篇发表文献

NMS-873 是一种通过高通量筛选识别的强效且特异性的小分子变构抑制剂，针对 ATP酶 VCP/p97（IC50 约为 0.03 uM）。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥735.00	现货
25mg	¥1,400.00	现货
50mg	¥2,590.00	现货
100mg	¥3,990.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用NMS-873发表的1篇文献

Yool Lee, .et al. , Sci Adv, 2021, 7

生物活性

Discription

NMS-873 is a potent and specific small molecule allosteric inhibitor of the ATPase VCP/p97 (IC50 ~0.03 uM), identified by a high-throughput screening.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12377
分子式	C27H28N4O3S2
分子量	520.67
CAS号	1418013-75-8
SMILES	CC1=C(C=CC(=C1)OCC2=NN=C(N2C3=CN=CC=C3)SC4CCCC4)C5=CC=C(C=C5)S(=O)(=O)C
其他名称	NMS873, NMS 873
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	98 mg/mL (188.22 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.21 mL	96.03 mL	192.06 mL
0.5 mM	3.84 mL	19.21 mL	38.41 mL
1 mM	1.92 mL	9.6 mL	19.21 mL
5 mM	0.38 mL	1.92 mL	3.84 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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