Nocodazole

Name: Nocodazole
SKU: A13219

目录号: A13219

microtubule 抑制剂

Nocodazole Chemical Structure

CAS NO. 31430-18-9

Nocodazole是微管抑制剂；抑制有丝分裂。也抑制自噬体-溶酶体融合。

库存：现货

规格	价格	数量
10 mg	￥ 350.00
25 mg	￥ 700.00
50 mg	￥ 1,260.00
100 mg	￥ 2,100.00
10mM * 1mL in DMSO	￥ 420.00

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产品详情

生物活性

Nocodazole是微管抑制剂；抑制有丝分裂。也抑制自噬体-溶酶体融合。

靶点信息

Microtubules (Cell-free assay)	Abl (Cell-free assay)	Abl (E255K) (Cell-free assay)	Abl (T315I) (Cell-free assay)
N/A	0.21 μM	0.53 μM	0.64 μM

溶解度 *

In vitro (25°C)	DMSO	6 mg/mL (19.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.19 mL	165.94 mL	331.87 mL
0.5 mM	6.64 mL	33.19 mL	66.37 mL
1 mM	3.32 mL	16.59 mL	33.19 mL
5 mM	0.66 mL	3.32 mL	6.64 mL

*The above data is based on the productmolecular weight 301.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13219
作用机制	Inhibitor (抑制剂)
M. Wt	301.32
Formula	C14H11N3O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	31430-18-9
SMILES	COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3