NPI-2358 (Plinabulin)
目录号: A10654
Microtubule 抑制剂
NPI-2358 是 NPI-2350 的合成类似物,NPI-2350 是从曲霉属(Aspergillus sp.)中分离出的天然产物,它能在 A549 人类肺癌细胞中 解聚微管。
Discription | NPI-2358 is a synthetic analog of NPI-2350, a natural product isolated from Aspergillus sp., which depolymerizes microtubules in A549 human lung carcinoma cells. | |||||
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Cell Research |
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目录号 | A10654 |
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分子式 | C19H20N4O2 |
分子量 | 336.4 |
CAS号 | 714272-27-2 |
SMILES | CC(C)(C)C1=C(N=CN1)/C=C\2/C(=O)N/C(=C\C3=CC=CC=C3)/C(=O)N2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 49 mg/mL (145.66 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.73 mL | 148.63 mL | 297.27 mL |
0.5 mM | 5.95 mL | 29.73 mL | 59.45 mL |
1 mM | 2.97 mL | 14.86 mL | 29.73 mL |
5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2