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NPI-2358 (Plinabulin)

NPI-2358 (Plinabulin)

Name: NPI-2358 (Plinabulin)
SKU: A10654

目录号: A10654

Microtubule 抑制剂

NPI-2358 (Plinabulin) Chemical Structure

CAS NO. 714272-27-2

NPI-2358 (Plinabulin)是NPI-2350的合成类似物，NPI-2350是从曲霉属（Aspergillus sp.）分离的天然产物，可解聚A549人肺癌细胞中的微管。

库存：现货

规格	价格	数量
5 mg	￥ 420.00
10 mg	￥ 560.00
50 mg	￥ 1,750.00
100 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 420.00

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生物活性

NPI-2358 (Plinabulin)是NPI-2350的合成类似物，NPI-2350是从曲霉属（Aspergillus sp.）分离的天然产物，可解聚A549人肺癌细胞中的微管。

靶点信息

Tubulin
9.8 nM-18 nM

溶解度 *

In vitro	DMSO	Warmed: 49 mg/mL (145.66 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.73 mL	148.63 mL	297.27 mL
0.5 mM	5.95 mL	29.73 mL	59.45 mL
1 mM	2.97 mL	14.86 mL	29.73 mL
5 mM	0.59 mL	2.97 mL	5.95 mL

*The above data is based on the productmolecular weight 336.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10654
作用机制	Inhibitor (抑制剂)
M. Wt	336.4
Formula	C19H20N4O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	714272-27-2
Synonyms	NPI2358
SMILES	CC(C)(C)C1=C(N=CN1)/C=C\2/C(=O)N/C(=C\C3=CC=CC=C3)/C(=O)N2