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NRA-0160 is a selective dopamine D4 receptor antagonist, with a Ki value of 0.48 nM and with negligible affinity for dopamine D2 receptor (Ki: >10000 nM), D3 receptor (Ki: 39 nM), rat 5-HT2A receptor (Ki: 180 nM) and rat α1 adrenoceptor (Ki: 237 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.75 mL | 113.76 mL | 227.52 mL |
| 0.5 mM | 4.55 mL | 22.75 mL | 45.5 mL |
| 1 mM | 2.28 mL | 11.38 mL | 22.75 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.55 mL |
*The above data is based on the productmolecular weight 439.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20128 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 439.52 |
| Formula | C24H23F2N3OS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 204718-47-8 |
| Synonyms | NRA0160, NRA 0160 |
| SMILES | O=C(C1=NC(C2=CC=C(F)C=C2)=C(CCN3CC/C(CC3)=C\C4=CC=CC(F)=C4)S1)N |
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